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NLRP3 expression by spinal microglia
NLRP3 expression by spinal microglia

Grace et al., 2016. Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation. Proc Natl Acad Sci USA. (accepted).

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TLR4-mediated vasodilation
TLR4-mediated vasodilation

Grace et al., 2014. Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and behavioral sequelae. Neuroscience, 280C, pp.299–317.

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Exercise attenuates macrophage infiltration/activation in the injured sciatic nerve
Exercise attenuates macrophage infiltration/activation in the injured sciatic nerve

Grace et al., 2016. Prior voluntary wheel running attenuates neuropathic pain. PAIN. (accepted)